Dindolyl Methane, or DIM as it’s more commonly referred to, is a well-known supplement for bodybuilders as well as other people who want to increase muscle growth. Recent studies have shown that DIM could pose health risks. DIM can cause liver damage if taken in excessive amounts. Kidney damage can also be a concern, and may lead to kidney failure. The possible long term health risks associated with DIM have many athletes and bodybuilders ask the question: should I use a supplement with DIM?
To increase the production of testosterone, most people take a diindolylmethane supplemental. It is well-known that testosterone functions as an androgen. This means that it can cause hormonal changes within the tissues. DIM has been proven in studies to mimic the effects of testosterone, along with other hormones. Since men produce more testosterone than women do, some manufacturers have added diindolylmethane to their products in order to make them more competitive in male circles. Men will react to products that mimic testosterone naturally.
As a result, numerous companies promote DIM as a cancer-fighter. Although diindolylmethane is effective in reducing the growth of tumors in laboratory animals it was administered orally to the animals. In order for humans to experience the same result diindolylmethane needs to be taken in large doses over a long time. The animals studied had no signs of cancer for many years. However, they all developed liver disease due to consuming too much diindolylmethane. To get a real glimpse of how DIM functions in the body, you should contact a medical practitioner.
According to the US National Institute of Environmental Health Safety and Security, the only way to demonstrate that DIM is effective in treating breast cancer is to perform an experiment where cells from healthy breast cancer cells are exposed to large doses of diindolylmethane over a period of time. Like all chemicals, there are both pros and cons to using it. Pros include the ability to mimic hormones. This allows you to make insulin that can stop the growth of cancer cells. The cons include the fact diindolylmethane is also able to produce the potentially harmful chemical DMSO. Learn more about dim diindolylmethane benefits here.
One of the most popular claims for diindolylmethane’s use as treatment for various illnesses is that it is an anti-cancer, natural, antibacterial and anti-fungal agent. These claims were rejected by the National Institute of Health after an exhaustive review of the supporting research. According to the Institute of Chemical Technology there were no experiments that supported this claim. In an in-depth study of the safety profile of the firestone, the Institute of Chemical Safety concluded that the evidence of pharmaceutical companies on the benefits to humans of diindolylmethane was not reliable.
Van der Goes, et. al. published their findings in a May 2021 issue of the Journal of Toxicology and Environmental Health. identified a variety of potential dangers related to the use of diindolylmethane, such as allergic reactions to the skin, asthma attacks, dizziness, headaches, and respiratory problems. The daily dose recommended for this chemical, which is roughly one tenth to one teaspoon was 0.2 milligrams. It isn’t clear what the concentration level is when it is compounded with other compounds. Because this substance has not been thoroughly examined, it isn’t considered safe at any point.
The abstract of the view suggests that the use of diindolylmethane (DIEM) in the treatment of cancer is based on the principle of inhibiting the intracellular inhibition of pyruvate’s pyruvate metabolite via flavenoids, and thus preventing accumulation of oxalates in renal tubule cells as well as Adenine granulocytes. However, metabiplicate toxicology studies didn’t provide convincing evidence that the consumption of this chemical results in an overdose. In June 1996, the Food and Drug Administration approved this drug as a prescribed drug. According to the FDA the company that manufactures firestone Tincture is currently completing two major tests in Europe and the United States.
The abstract of the view also indicates the use of diindolylmethane in cancer treatment is based on the concept of inhibiting intracellular inhibition through flavenoids that regulate pyruvate metabolism and thus hindering the accumulation of oxalates and adenine in the renal tubule cells. However, the drug metabiplicate studies failed to present convincing evidence that consumption of this chemical causes an overdose. The Food and Drug Administration approved this substance as a prescribed drug in June 1996. According to the FDA the company that makes firestone tincture is in the process of completing two major studies – one in Europe and one in the United States. According to the FDA, the manufacturer of firestone tincture is in the process of conducting two major trials in Europe and one in the United States.
